Problems with the
Formation of Nucleic Acids
lSee Robert Shapiro, Origins, and his article ÒImprobability of Prebiotic Nucleic Acid SynthesisÓ:
lWe get low yields even with pure chemicals.
lWe need drastically different conditions for various steps re/ acidity, temperature, catalysts.
lWe encounter competing reactions.
lHow do these nucleotides find each other?